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Meningitis Case Definitions and Confirmation

Condition Code Case Definition/Case Classification Lab Confirmation
Aseptic meningitis
10010
A syndrome characterized by acute onset of meningeal symptoms (stiff neck, fever, and headache), cerebrospinal fluid pleocytosis (excessive lymphocytes), with no laboratory evidence of bacterial or fungal organisms. Aseptic meningitis is a syndrome of multiple etiologies, but many cases are caused by a viral agent.

Confirmed: A clinically compatible illness diagnosed by a physician as aseptic meningitis, with no laboratory evidence of bacterial or fungal meningitis; or a viral isolate from cerebrospinal fluid; or a viral isolate from blood with a clinically compatible illness diagnosed by a physician

  • Laboratory Confirmation:
  • A viral isolate from cerebrospinal fluid, or
  • A viral isolate from blood with physician diagnosis of aseptic meningitis
  • Supportive of Clinical Diagnosis:
  • No growth in CSF or blood cultures
  • CSF with test results characteristic of viral meningitis
Bacterial and Other meningitis
10650
Bacterial meningitis manifests most commonly with fever, headache, and a stiff neck; the disease may progress rapidly to shock and death. However, other manifestations may be observed.

Confirmed: A clinically compatible case that is laboratory confirmed
Probable: A clinically compatible case diagnosed by a physician as bacterial meningitis without culture confirmation

Isolation of a bacterial species, fungus, or parasite from the cerebrospinal fluid or a clinically compatible case accompanied by a positive blood culture